第33页(第2页)
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经坏死了,胃肠粘膜也出现了毒物刺激的病变。我知道这些病变不符合&1dquo;中毒型菌
痢”的病理特征,只有在毒物的作用下,才有可能出现这样的结果
会是什么毒物导致死者中毒死亡呢?
为了证明毒物的类别,我提取了死者的胆汁、心血、胃肠容物、肝、肾、脑等
脏器。我把它们送到了毒物化验室,要求检验员作系统的毒物分析。
可是,化验结果为&1dquo;常见毒物阴性”,结论是&1dquo;尸体内未检出毒物”。
中毒致死,体内却检不出毒物,会不会是由于毒物在体内已经生了代谢的结
果?
毒物进入人体后,在细胞内某种酶的作用下,将生化学变化,使得一种物质
变成了另外一种物质,这就是毒物在机体内的代谢。
不同的毒物,代谢的程度和方式也不同。有些毒物代谢过程很快,当毒物在体
内生作用导致人体中毒后,毒物即刻迅代谢,又很快排泄到体外。这样,在中
毒致死的尸体中就很难找出毒物来。
使安苗中毒的毒物很可能具有这样的特征。
我进一步在&1dquo;生物碱”这个范畴中选择相近的目标。
含有生物碱的毒物种类繁多,像乌头属、钩吻、曼陀罗、马钱子、芽的马铃
薯&he11ip;&he11ip;都是,到底哪一种更接近目标呢?
我在这些毒物中逐一筛选,范围渐渐地缩小,目标最终瞄向了&1dquo;秋水仙碱”。
有资料记载:&1dquo;秋水仙碱”存在于秋水仙花内,是天然生物碱,含量约为o。1%,
为有效的细胞有丝分裂抑制剂,毒性极强,口服6毫克即可死亡。&1dquo;秋水仙碱”在
人体内由于水解作用代谢很快,排泄也很快,达到最高浓度后绝大部分代谢并从尿
中迅排出,中毒后在人体内含量极微。
&1dquo;秋水仙碱”对中枢神经系统的作用很强。中毒症状有恶心、呕吐、腹泻、
烧、精神失常、血尿、肾小管坏死,最后因严重循环衰竭而死亡。
再次化验,目标直指&1dquo;秋水仙碱”,方法是微量分析法。化验结束时,一切都
明白了:尸体的血液中确实含有&1dquo;秋水仙碱”,只是含量极微,每升中才5微克。
法医鉴定书很快拟出,结论是:安苗,死于&1dquo;秋水仙碱”中毒。
当安苗的死因被确定后,最紧张的要算安苗的上司——市建行某分行信贷科的
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